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Regenerative Medicine and Innovative Technologies

Research on technological innovations develops advanced tools such as organoids, stem cells, gene editing, and bioprinting to create increasingly personalized therapies.
Our Scientists

Nicola Elvassore

  • Principal Investigator
  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

Cecilia Laterza

  • Principal Investigator
  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

Onelia Gagliano

  • Principal Investigator
  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

Francesco Chemello

  • Principal Investigator
  • Medicina Rigenerativa e Tecnologie Avanzate, Fisiopatologia e Rigenerazione Muscolare

Latest Discoveries

Early Reprogramming Intermediates Enable Direct Neuronal Conversion Via NGN2.

2026 - Journal of Molecular Neuroscience

Onelia Gagliano

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

In situ tailored confining microenvironment for lung cancer spheroids

2025 - Mater Today Bio

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

Quantifying mechanical forces during vertebrate morphogenesis

2024 - Nature Materials

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition

2024 - Developmental Cell

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals

2024 - Journal of Clinical Investigation

Marco Sandri

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease

2024 - Biochimica et Biophysica Acta: Molecular Basis of Disease

Carlo Viscomi

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

The inhibition of inner mitochondrial fusion in hepatocytes reduces NAFL and improves metabolic profile during obesity by modulating bile acid conjugation.

2023 - Cardiovascular Research

Luca Scorrano

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Ricerca Oncologica Avanzata

Gene therapy for mitochondrial disorders

2024 - Journal of Inherited Metabolic Disease

Carlo Viscomi

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

White Matter Tract Density Index Prediction Model of Overall Survival in Glioblastoma

2023 - Nat. Commun

Maurizio Corbetta

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Ricerca Oncologica Avanzata, Cervello e Sistema Nervoso

Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation.

2023- Cells

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

Drosophila Mpv17 forms an ion channel and regulates energy metabolism

2023 - iScience

Carlo Viscomi

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription.

2023 - Nature Communications

Konstantinos Lefkimmiatis

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Ricerca Oncologica Avanzata

NGN2-based neuronal programming of hiPSCs in an automated microfluidic platform

2023 - Biochemical and Biophysical Research Communications

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures

2023 - Nature Communications

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

Cellular population dynamics shape the route to human pluripotency

2023 - Nature Communications

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate, Cervello e Sistema Nervoso

Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry.

2023 - Developmental Biology

Nicola Elvassore

Principal Investigator

  • Medicina Rigenerativa e Tecnologie Avanzate

Support Our Research

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Support Our Research

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