Mario Bortolozzi

Researcher funded by Fondazione Telethon – MultiRound Grant
Ricercatore non strutturato
Group members
Research

Mario Bortolozzi studies the molecular mechanisms underlying disorders of the nervous system, with particular focus on the ion channels involved in Charcot-Marie-Tooth neuropathy and on the neurotoxic effects of environmental contaminants such as PFAS.

Publications
  1. Calcium Regulation of Connexin Hemichannels.

    Bayraktar E, Lopez-Pigozzi D, Bortolozzi M. Int J Mol Sci. 2024 Jun 15;25(12):6594. doi: 10.3390/ijms25126594.

  2. Special Issue “Gap Junction Channels and Hemichannels in Health and Disease”.

    Rijtano B, Bortolozzi M. Int J Mol Sci. 2025 Sep 23;26(19):9264. doi: 10.3390/ijms26199264.

  3. New perspectives for gene therapy of the X-linked form of Charcot-Marie-Tooth disease.

    Caballé RB, Bortolozzi M. Mol Ther Methods Clin Dev. 2024 Jan 12;32(1):101184. doi: 10.1016/j.omtm.2023.101184. eCollection 2024 Mar 14.

  4. Measuring Connexin Hemichannel Opening in Response to an InsP3-Mediated Cytosolic Ca2+ Increase.

    Bayraktar E, Bortolozzi M. Methods Mol Biol. 2024;2801:189-197. doi: 10.1007/978-1-0716-3842-2_14.

  5. Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.

    Qi C, Lavriha P, Bayraktar E, Vaithia A, Schuster D, Pannella M, Sala V, Picotti P, Bortolozzi M, Korkhov VM. Sci Adv. 2023 Sep;9(35):eadh4890. doi: 10.1126/sciadv.adh4890. Epub 2023 Aug 30.

Curriculum

2008

Phd in Bioscience - Padua University

2008 - 2010

Postdoctoral Research Fellow - Padua University

2012 -2013

Researcher - Oxford University

2010 - 2017

Researcher - Padua University

2013 - 2023

Principal Investigator - VIMM

2017 - present

Associate Professor - Padua University

Selected Awards

2005

Travel grant- 9 th “Mechanics of Hearing” Workshop, Portland

2007

Travel grant - 44 th Workshop in Inner Ear Biology, London (UK)

2008

Travel grant - 9 th “International Conference on Systems Biology”, Göteborg

2012

Poster award to “Cardiac and Respiratory Physiology” meeting, Manchester (UK)