More specifically, Dr. Omori’s goal is to identify a new therapeutic approach for patients affected by prostate tumors that do not resolve with the conventional administration of antiandrogenic drugs. The research focus is therefore on the role of mitochondria: essential organelles for the metabolic process and energy supply, already known for their alteration in other types of cancer.
The researchers will therefore proceed with a comparison between normal prostate cells and cancerous cells to understand the differences in the metabolism and activation of some key genes linked to the tumor. “In particular, we will study the role of the mitochondrial protein Opa1 which, with pharmacological inibition , appears to be able to reduce tumor growth and severity”.
The grants award ceremony to researchers “of the highest scientific profile, innovators and for the most part women” will take place on Thursday 25 March from 18.30 to 19.30. This year the event will take place open-door, in streaming through the channels of the Umberto Veronesi Foundation and on StartupItalia. You can register for the event to stay informed about the initiative.